Defended Ph.D. Theses and Current Ph.D. Students

Defended

Title: Identification of biomarkers and the development of combination polymer conjugates in metastatic prostate cancer.
PhD Student: Antoni Serrano Martí.
Entity: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies
Date: 13/05/2025. Mark: Excellent Cum Laude with an option for the Extraordinary Ph.D. prize. International PhD

Title: Mitochondria-targeted ROS mediated polypeptide-drug conjugate delivery platforms.
PhD Student: Camilla Pegoraro (Co-supervised with Inma Conejos-Sánchez)
Entity: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies
Date: 16/04/2025. Mark: Excellent Cum Laude with an option for the Extraordinary Ph.D. prize. International PhD

Title: Development of Advanced Preclinical Breast Cancer Models for Nanomedicines Development and Functional Biomarker Identification
PhD Student: Paz Boix-Montesinos (Co-supervised with Ana Armiñán)
Entity: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies
Date: 12/09/2024 Mark: Excellent Cum Laude with an option for the Extraordinary Ph.D. prize. International PhD

Title: Development of Mitochondria Metabolomic Analysis for the Preclinical Characterization of the Impact of New Antitumoral Therapies
PhD Student: Inés Domingo (FPU)(Supervised with Martina Palomino Schätzlein and Antonio Pineda Lucena)
Entity: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies
Date: 19/04/2024 Mark: Sobresaliente

Title: Brain drug delivery using polymer therapeutics as intranasal platform towards paediatric glioma treatment
PhD Student: Tetiana Melnyk (AECC Grant) (Co-supervised with Dr. Conejos-Sanchez)
Entity: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies
Date: 07/03/2024 Mark: Sobresaliente

Title: Development of analytical techniques for characterization of polymer drug conjugates in biological fluids
PhD Student: Snežana Đorđević
University: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies
Date: 24/05/2023 Mark: Sobresaliente mención Cum Laude y Mención Internacional (Opta a Premio Extraordinario) (Maximum mark)

Title: Inflammatory Tumor Microenvironment as Target in the Design of Nanoconjugates for the Treatment of Advanced Breast Cancer (InflaNanoTarget)
PhD Student: Paula Soriano Teruel (Supervised with Mar Orzáez)
Entity: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies
Date: 27/01/2023 Mark: Excellent Cum Laude

Title: Design of novel targeted polymer therapeutics as combination therapy for the treatment of brain metastasis-overcoming the blood brain barrier
PhD Student: Fernanda Rodríguez Otormín (AECC Grant) (Co-supervised with Dr. Duro-Castaño)
University: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies
Date: 07/04/2022 Mark: Sobresaliente mención Cum Laude

Title: Polypeptidic carriers for the topical delivery of actives and therapeutics
PhD Student: Daniel Morelló Bolumar
Entity: Polypeptide Therapeutic Solutions SL / CIPF
Date: 21/07/2021
Mark: Excellent Cum Laude

Title: Development of Polymer-based Therapeutics for the Treatment of Castration Resistant Prostate Cancer
Student: Sonia Vicente-Ruiz (Co-supervised with Dr. Ana Armiñán)
Date: 15/07/2020
Mark: Excellent Cum Laude

Title: Design of Polypeptide-based self-assembled therapeutics for Personalised Medicine in Breast cancer
Student: Oleksandr Zagorodko (Co-supervised with Dr. Vicent Nebot)
Date: 11/05/2020
Mark: Excellent Cum Laude with an option for the Extraordinary Ph.D. prize (Maximum mark)

Project Title: “DEVELOPMENT OF POLYPEPTIDE BASED THERAPEUTICS FOR TOPICAL DELIVERY”
Doctorate Student: Irene Dolz Pérez
Date: 26/11/19
Mark: Sobresaliente mención Cum Laude y Mención Internacional

Project Title: “Polymer-based combination conjugates for the treatment of triple negative breast cancer: From rational design to Preclinical evaluation”
Doctorate Student: Juan José Arroyo Crespo
Date: 12th November 2018
Mark: Excelente Cum Laude por unanimidad

Project Title: Well-defined polyglutamates as non-viral vectors for cytosolic delivery
Doctorate student: Amaya Niño Pariente (FPI grant)
Date: 24th July 2017
Mark: Excelente cum Laude por unanimidad

Project Title: Desarrollo de Nanomedicinas y soportes poliméricos para la regeneración de tejidos y/o diferenciación de células madre
Doctorate Student: Gabriela de Jesús Rodríguez Escalona (Co-supervised Prof. M. Monleón)
Date: Feb 2016

Project Title: Polyglutamates as carriers for the treatment of neurodegenerative disorders
Doctorate Student: Aroa Duro Castaño (FPU grant)
Date: 8 October 2015
Mark: Excelente cum Laude por unanimidad

Project Title: Defining new biotypes in Prostate Cancer for diagnosis, prognosis and therapeutic intervention
Doctorate Student: Irene Casanova-Salas (FIS grant) (Co-supervised with Dr JA López-Guerrero and J. Rubio)
Date: 30 June 2015
Mark: Excelente cum Laude por unanimidad

Project Title: Polymer-based Combination conjugates for the treatment of Breast Cancer
Doctorate Student: Coralie Deladriere (FPI grant) (Co-supervised with Rut Lucas Domínguez)
Date: 17 September 2013
Mark: Excelente cum Laude por unanimidad

Project Title: Rational design of polymer conjugates for the treatment of neurological disorders
Doctorate Student: Inmaculada Conejos Sánchez (FPU grant)
Date: 30 July 2013
Mark: Excelente cum Laude por unanimidad (2º award the best PhD thesis of the SPLC-CRS)

Project Title: pH-responsive Polyacetals for the treatment of Hormone-dependent cancer
Doctorate Student: Vanessa Giménez Navarro
Date: 30 November 2012.
Mark: Apto cum Laude por unanimidad (Extraordinary PhD award in Biomedicine)

Current Students

Title: Synergistic approach for neurodegenerative disorder treatments using versatile polypeptide-based conjugates.
PhD Student: Maria Ibañez (co-supervised M Medel) (FPI grant)
Entity: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies
To be Defended in 2026

Title: Design of Polymer Conjugates for Glioblastoma treatment.
PhD Student: Amina Benaicha (co-supervised I Conejos-Sánchez) (AECC-CV PhD grant).
Entity: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies.
To be Defended in 2027

Title: Design of star-shaped tripeptides with fibrillar organization in combination with stem cell therapy for SCI treatment.
PhD Student: Karolina Gwizdała.
Entity: Centro de Investigación Príncipe Felipe Dpt: Advanced Therapies.
To be Defended in 2027

Title: Low Mw peptidic gelators for Biomedical applications.
PhD Student: Martina LaMana (MSCA ITN MULTISMART network).
Entity: Universitat Jaume I (UJI).
To be Defended in 2027

Title: Spatial Transcriptomics and Cell Communication Models applied to tissue regeneration and treatment in Spinal Cord Injury with Precision Nanomedicine.
PhD Student: Margarita Gubina (Prometeo Cells2Spain network).
To be Defended in 2027

Title: A Multimodal Precision Polypeptide-based Nanoplatform to Treat and Monitor Metastatic Castration Resistance Pca.
PhD Student: Nerea Manzano (FPI, PID2023).
To be Defended in 2028

Title: NanoInBrain Platform Applied for the treatment of Brain Metastasis from Breast Cancer.
PhD Student: Leire Miguela (ACIF grant).
Entity: Centro de Investigación Príncipe Felipe.
Defended: 2028

Precision ImmuneNanoTherapy targeting tumor-immune-stroma interactions against pancreatic cancer.
PhD Student: Carla Ortuño (La Caixa Health Research-PINT).
To be Defended in 2028

TITLE: Development of novel polymeric carriers as non-viral gene delivery vectors in the form of polyplexes.
PhD Student: Valentina Zazza.
To be Defended in 2029

Title: Design of polypeptide-based nanosystems with inherent mitochondrial tropism for oligonucleotide delivery.
PhD Student: Tanibet Alba O’Reilly.
To be Defended in 2029

Title: Development and Preclinical Validation of a Multivalent Nanovaccine for the Treatment of Peritoneal Carcinomatosis.
PhD Student: María Caballer Sanchís.
To be Defended in 2029

Title: Innovative dual nano-immunotherapy for pancreatic ductal adenocarcinoma (PDAC)
PhD Student: Tiago André Silva Fidalgo (FCT grant, co-supervised with prof Florindo and Prof Graça. Entity: University of Lisboa.
To be Defended in 2029