Patents

MJ. Vicent, I. Conejos-Sánchez, C. Pegoraro, E. Karpova, G Sogorb, C Felip, VJ Nebot, P. Schwille, Y. Qutbuddin Polyproline-based block copolymers. Application no.: EP23382668.4; Filing date: June 29, 2023 PTS SL, CIPF, Max-Planck-Gesellschaft zur Förderung Der Wissenschaften E.V.

L. Herrera, I. Dolz, C. Felip, M.J. Vicent, V. J. Nebot. Star-shaped PAsp-oligoamine derivatives. Application no.: EP21382666.2 Filing date: July 22, 2021. Polypeptide Therapeutic Solutions S.L.

Polymeric conjugates and uses there of

Application number: EP19382225.1.

Application date: 28 March 2019

CROSS POLYMERS COMPOSED OF POLYSACCHARIDES AND POLYAMINO ACIDS, AND USES THEREOF

The present invention relates to cross polymers composed at least of polysaccharides and polyamino acids, and more particularly to hydrogels composed of said cross polymers. The invention also relates to a process for preparing them, as well as their use in the delivery of active agents for pharmaceutical, diagnostic and/or dermo-cosmetic applications.

  • Pub. No.:             WO/2019/020344             International Application No.:     PCT/EP2018/068327
  • Publication Date:              31.01.2019           International Filing Date:              06.07.2018
  • Chapter 2 Demand Filed:              02.04.2019
  • Applicants:          POLYPEPTIDE THERAPEUTIC SOLUTIONS S.L. [ES/ES]; Centro de Investigación Príncipe Felipe Avenida Eduardo Primo Yúfera, 3 46012 Valencia, ES
  • Inventors: DOCÓN MARÍA JESÚS, Vicent, NEBOT CARDA VICENT, Josep, MORELLÓ BOLUMAR, Daniel, ENGLAND RICHARD, Marc
  • Priority Data:      17382498.8                          26.07.2017

Cross-linked Star-shaped self-assembled polyglutamates and its use as carriers in
biomedical applications.

Inventors/authors/obtainers: Vicent J. Nebot; Aroa Duro-Castaño; Maria J. Vicent.
Holding institution: Centro de Investigación Príncipe Felipe.
Application number: European patent EP3127938A1
 Priority country: Spain
Date: 08/08/2015.

POLYMER DRUG CONJUGATES FOR THE TREATMENT OF AMYLOIDOSIS

The present invention is referred to novel polymeric conjugates to which at least it is linked a fibril disruptor agent and/or a aggregates blocking agent, and additionally a targeting moiety and/or a probe for therapy and diagnosis. In the polymer-drug conjugate, the polymeric platform transports at least one bioactive agent, selected from the group of anthracyclines antibiotics which includes tetracycline, rolitethracycline, minocycline and/or doxycycline and their derivatives, etc…, able to disaggregate or break the amyloid fibrils and/or block the aggregates. This conjugate could contain in its structure one or several targeting moieties, which will provide an effective targeting of the polymer-drug conjugate to the selected diseased area for drug activity, increasing the therapeutic efficacy in the treatment of amyloidosis related diseases, including amyloidosis related to polyneuropathic disorders and neurodegenerative diseases like FAP and AD.

  • Pub. No.:             WO/2014/187654             International Application No.:     PCT/EP2014/058856
  • Publication Date:              27.11.2014           International Filing Date:              30.04.2014
  • Chapter 2 Demand Filed:              17.03.2015
  • Applicants: FUNDACION DE LA COMUNIDAD VALENCIANA “CENTRO DE INVESTIGACIONES PRINCIPE FELIPE” [ES/ES]; Avda. Eduardo Primo Yúfera, 3 E-46012 Valencia, ES
  • Inventors: VICENT DOCÓN, María Jesús; CONEJOS SANCHEZ, Inmaculada;
  • Priority Data:      13382184.3                          20.05.2013                           EP

Name: Sintesis controlada de poliglutamatos con baja polidispersidad y arquitecturas versátiles

Description of qualities: Generación Spin Off Polypeptide Therapeutic Solutions SL
Type of industrial property: Patent of invention
Inventors/authors/obtainers: María J. Vicent; Matthias Barz; Aroa Duro; Inma Conejos; Fabiana Canal; Richard England
Holding institution: Centro de Investigación Príncipe Felipe
Application number: PCT/ES2012/070740
Priority country: Spain
Date: 24/10/2011
Conferral date: 21/10/2012
Spanish patent: Yes
PCT patent: Yes
Licences: Yes
Commercial use, exclusive: Yes
Creating an innovative enterprise: Yes Results: Success

Name: Novel conjugates of polymers having a therapeutically active agent and an angiogenesis targeting moiety attached thereto and uses thereof in the treatment of angiogenesis related diseases

Description of qualities: En proceso de licencia a farmacéutica
Type of industrial property: Patent of invention
Inventors/authors/obtainers: Ronit Satchi-Fainaro; María Jesús Vicent Docón
Holding institution: Centro de Investigación Príncipe Felipe and Tel Aviv University
Application number: WO/2009/141826
Priority country: United States of America
Date: 22/05/2008
Conferral date: 26/11/2009
Patent number: WO/2009/141826
EU patent: Yes
International non-EU patent: Yes PCT patent: Yes
Extended to: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF,CG , CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).

Name: Novel Nanoconjugates for the treatment of sepsis.

Inventors/authors/obtainers: (in order of authorship): María J. Vicent; Enrique Pérez-Payá; Angel Messeguer; Laura Cascales
Holding institution: Centro de Investigación Príncipe Felipe y CSIC
Application number: PCT/2010/30218
Priority country: Spain
Date: 28/05/2009

Name: Polymer conjugate compounds for the inhibition of apoptosis.

Type of industrial property: Patent of invention
Inventors/authors/obtainers: E. Pérez-Payá; À. Messeguer; M.J. Vicent; G. Malet; M. Orzáez; L. Mondragón; G. Sanclimens; A. Moure
Holding institution: Centro de Investigación Príncipe Felipe y CSIC
Application number: WO/2008/141762
Priority country: Spain
Date: 21/05/2007
Conferral date: 27/11/2008
PCT patent: Yes
Licences: Yes
Companies: Salvat Labs.
Commercial use, exclusive: Yes
Extended to: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European
Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).

Name: Composición farmacéutica para inhibir la apoptosis

Type of industrial property: Patent of invention
Inventors/authors/obtainers: E. Pérez-Payá; À. Messeguer; M.J. Vicent; G. Malet; M. Orzáez; L.Mondragón; G. Sanclimens; A. Moure
Holding institution: Centro de Investigación Príncipe Felipe y CSIC
Application number: WO/2007/060524
Priority country: Spain
Date: 01/06/2005
Conferral date: 22/11/2006
Spanish patent: Yes EU patent: Yes
International non-EU patent: Yes PCT patent: Yes
Licences: Yes
Companies: Laboratorios Salvat, S.A.
Commercial use, exclusive: Yes
Extended to: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM,GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA,MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).